Jennifer Aniston is hitting back at comments about politicians who are "childless cat ladies" made by Republican vice presidential candidate Sen. JD Vance, which have recently gone viral.

"The Morning Show" star, 55, on Wednesday took to her Instagram Stories and posted a screenshot of a social media post in which Ron Filipkowski, editor-in-chief of the MeidasTouch Network, shared a 2021 "Tucker Carlson Tonight" interview clip with Vance.

"JD Vance says women who haven’t given birth like Kamala Harris are 'childless cat ladies who are miserable at their own lives,' and have 'no direct stake' in America," Filipkowski wrote alongside the 28-second clip.

"I truly can't believe this is coming from a potential VP of the United States," Aniston wrote. "All I can say is… Mr. Vance, I pray that your daughter is fortunate enough to bear children of her own one day. I hope she will not need to turn to IVF as a second option. Because you are trying to take that away from her, too."

What did JD Vance say about 'childless cat ladies?'

The conversation between Vance and Carlson aired on Fox News in July 2021, when Vance was running for Ohio's U.S. Senate seat.

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"We are effectively run in this country … by a bunch of childless cat ladies who are miserable at their own lives and the choices that they’ve made, and so they wanna make the rest of the country miserable, too," Vance told Carlson. "It's just a basic fact. You look at Kamala Harris, Pete Buttigieg, AOC (Alexandria Ocasio-Cortez), the entire future of the Democrats is controlled by people without children."

He added, "And how does it make any sense that we've turned our country over to people who don't really have a direct stake in it?"

Harris has two stepchildren with her husband, Second Gentleman Douglas Emhoff. Transportation Secretary Buttigieg and husband Chasten welcomed twins weeks after Vance's interview.

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Jennifer Aniston said fertility struggles were a 'challenging road'

In 2022, the "Friends" star opened up about her fertility struggles for the first time in a cover story for Allure.

"I was trying to get pregnant," she said, referring to when she was in her late 30s into her 40s. "It was a challenging road for me, the baby-making road."

"All the years and years and years of speculation... It was really hard," she added. "I was going through IVF, drinking Chinese teas, you name it. I was throwing everything at it. I would’ve given anything if someone had said to me, 'Freeze your eggs. Do yourself a favor.' You just don't think it. So here I am today. The ship has sailed."

She added, "I just cared about my career. And God forbid a woman is successful and doesn’t have a child. And the reason my husband left me, why we broke up and ended our marriage, was because I wouldn’t give him a kid. It was absolute lies. I don’t have anything to hide at this point."

Aniston was married to Brad Pitt from 2000 to 2005 and Justin Theroux from 2015 to 2017.

Contributing: Kinsey Crowley