A woman was rescued from a tractor trailer after being involved in a four-vehicle accident that left the truck dangling precariously from the Clark Memorial Bridge over the Ohio River in Louisville, Kentucky on Friday.

Louisville Fire Chief Brian O'Neill said the woman was rescued from the cabin at 12:45 p.m., about 40 minutes after the collision occurred.

Two other people involved in the accident have been transported to an area hospital with life-threatening injuries, Louisville Metro Police spokesperson Aaron Ellis said in a statement.

The bridge, which connects Kentucky and Southern Indiana, was closed to traffic while LMPD and the Kentucky Transportation Cabinet assess damage and clear the scene.

The bridge was not expected to reopen before Saturday morning, Ellis said.

'It's tremendously lucky that it didn't go over'

Officials have not yet determined the cause of the accident, but O'Neill said the rescued driver was "extremely lucky" her truck did not fall into the river.

"The position that it's in ... it's tremendously lucky that it didn't go over," he said.

The chief said Louisville's rescue team trains regularly to respond to various situations, practicing rescues from bridges, high-rises and other points. However, putting the training to use is "extremely unique."

"This is a once-in-a-career type of thing," he said.

Firefighter Bryce Carden was responsible for getting a harness to the trailer's driver and lifting her to safety.

O'Neill called Carden "one of the nicest, happiest guys that you'll ever want to meet in your life. And he is the exact right person to put down there to try to keep the patient calm and very cool and collected, to understand that she's in safe hands."

O'Neill also applauded the driver, who he said "held it together like a champ." Firefighters were able to speak with the driver through an open window while preparing equipment for the rescue, and O'Neill said she remained calm until she reached the ground.

"She was just praying. She was praying a lot, and I prayed with her," Carden said.

Reach reporter Bailey Loosemore at [email protected], 502-582-4646 or on Twitter @bloosemore.